245 Side effects of oral antibiotics in small children with cystic fibrosis

Prevalence of Cystic Fibrosis Trans-membrane Conductance Regulator Gene common mutations in children with cystic fibrosis in Isfahan, Iran

Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations. Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary ped...

Bronchial response to nebulized antibiotics in children with cystic fibrosis.

Nebulized antibiotics are being used increasingly in children with cystic fibrosis. We assessed the effect of nebulized antibiotic solutions of varying tonicity on lung function in 12 children aged 5-15 yrs with cystic fibrosis. Baseline forced expiratory volume in one second and (FEV1) was measured, followed by a single nebulization of normal saline (272 mosmol.kg-1), tobramycin (248 mosmol.kg...

Antibiotics in Cystic Fibrosis.

IN cystic fibrosis the main problem is the susceptibility of the children to respiratory infection. The clinical course of the untreated case is one of repeated respiratory infections followed by persistent pulmonary sepsis, and later death. Severe attacks may occur in the first weeks or months of life, or less commonly, years may pass with no, or minimal symptoms referable to the chest. Upper ...

Nebulised bronchodilators, antibiotics and rhDNase for children with cystic fibrosis.

Bronchodilators syndrome occurring in association with ipratropium. Nebulised bronchodilators are used extensively in children with cystic fibrosis, but in many Optimal dosage regimens for b agonists have not been investigated, and doses given to chilinstances this use is not yet based on objective evidence of clinical benefit. dren with cystic fibrosis are usually similar to those used in asth...

Side-effects to antibiotics in cystic fibrosis: dental changes in relation to antibiotic administration.